Assay Detail
Binding
CHEMBL5140886
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Escherichia coli FimH assessed as dissociation constant by SPR analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Type 1 fimbrin D-mannose specific adhesin (CHEMBL4837) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
Publication
Small Carbohydrate Derivatives as Potent Antibiofilm Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.53 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1170455 | — | — | 1 | 8.30 |
| CHEMBL195368 | — | — | 1 | 5.66 |
| CHEMBL365590 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1170455 | — | Kd | = | 5.0 | nM | 8.30 |
| CHEMBL195368 | — | Kd | = | 2200.0 | nM | 5.66 |
| CHEMBL365590 | — | Kd | = | 2300.0 | nM | 5.64 |