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Assay Detail

CHEMBL5140965

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against mouse SC-3 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type SC-3
Confidence 1 — Organism
Curated By Autocuration

Target

SC-3 (CHEMBL614897)
Type CELL-LINE
Organism Mus musculus

Publication

Therapeutic Strategies to Target the Androgen Receptor.
Xiang W, Wang S.
J Med Chem (2022) 65 : 8772 -8797
PubMed 35786895 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.41 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3622589 1 6.75
CHEMBL518945 1 6.36
CHEMBL2441094 1 6.12

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3622589 IC50 = 180.0 nM 6.75
CHEMBL518945 IC50 = 440.0 nM 6.36
CHEMBL2441094 IC50 = 750.0 nM 6.12