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Assay Detail

CHEMBL5140973

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to GABA A receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

GABA-A receptor; anion channel (CHEMBL2093872)
Type PROTEIN COMPLEX GROUP
Organism Homo sapiens

Publication

Therapeutic Strategies to Target the Androgen Receptor.
Xiang W, Wang S.
J Med Chem (2022) 65 : 8772 -8797
PubMed 35786895 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1082407 ENZALUTAMIDE 4.0 1 5.52
CHEMBL3183409 APALUTAMIDE 4.0 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1082407 ENZALUTAMIDE IC50 = 3000.0 nM 5.52
CHEMBL3183409 APALUTAMIDE IC50 = 3000.0 nM 5.52