Assay Detail
Binding
CHEMBL5142006
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Inhibition of monkey DHODH
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Macaca mulatta |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
<i>N</i>-Heterocyclic 3-Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.04 | 9.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5193821 | — | — | 1 | 9.27 |
| CHEMBL5193591 | — | — | 1 | 8.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5193821 | — | IC50 | = | 0.54 | nM | 9.27 |
| CHEMBL5193591 | — | IC50 | = | 1.6 | nM | 8.80 |