Assay Detail
Functional
CHEMBL5143221
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Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth and measured after 72 hrs resazurin reduction assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Echiumin E, an Aryl Dihydronaphthalene Lignan from the Australian Invasive Plant Paterson's Curse (<i>Echium plantagineum</i>).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.61 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92 | DOCETAXEL ANHYDROUS | 4.0 | 1 | 9.22 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 8.00 |
| CHEMBL5175097 | — | — | 1 | - |
| CHEMBL5198157 | — | — | 1 | - |
| CHEMBL5200512 | — | — | 1 | - |
| CHEMBL324842 | ROSMARINIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92 | DOCETAXEL ANHYDROUS | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL5175097 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5198157 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5200512 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL324842 | ROSMARINIC ACID | IC50 | > | 10000.0 | nM | - |