Assay Detail
Binding
CHEMBL5143946
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Binding affinity to VBC (unknown origin) using FAM-DEALA-Hyp-YIPD as substrate by fluorescence polarization assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
An efficient strategy for digging protein-protein interactions for rational drug design - A case study with HIF-1α/VHL.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 6.77 | 7.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5182075 | — | — | 1 | 7.20 |
| CHEMBL5207858 | — | — | 1 | 7.09 |
| CHEMBL5176409 | — | — | 1 | 6.78 |
| CHEMBL5204442 | — | — | 1 | 6.72 |
| CHEMBL5190175 | — | — | 1 | 6.71 |
| CHEMBL3344081 | — | — | 1 | 6.69 |
| CHEMBL5208302 | — | — | 1 | 6.65 |
| CHEMBL5172140 | — | — | 1 | 6.64 |
| CHEMBL5173605 | — | — | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5182075 | — | IC50 | = | 63.0 | nM | 7.20 |
| CHEMBL5207858 | — | IC50 | = | 81.0 | nM | 7.09 |
| CHEMBL5176409 | — | IC50 | = | 166.0 | nM | 6.78 |
| CHEMBL5204442 | — | IC50 | = | 189.0 | nM | 6.72 |
| CHEMBL5190175 | — | IC50 | = | 193.0 | nM | 6.71 |
| CHEMBL3344081 | — | IC50 | = | 204.0 | nM | 6.69 |
| CHEMBL5208302 | — | IC50 | = | 223.0 | nM | 6.65 |
| CHEMBL5172140 | — | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL5173605 | — | IC50 | = | 350.0 | nM | 6.46 |