Assay Detail
Binding
CHEMBL5144928
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Inhibition of PI4Kalpha (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification and optimization of a novel series of selective PIP5K inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.97 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5206569 | — | — | 1 | 5.24 |
| CHEMBL5171272 | — | — | 1 | 4.89 |
| CHEMBL5191668 | — | — | 1 | 4.77 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5206569 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL5171272 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL5191668 | — | IC50 | = | 17000.0 | nM | 4.77 |