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Assay Detail

CHEMBL5146294

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK9 (unknown origin) using YSPTSPSYSPTSPSYSPTSPS peptide as substrate in presence of ATP by luciferase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 9 (CHEMBL3116)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Lessons Learned from Past Cyclin-Dependent Kinase Drug Discovery Efforts.
Xie Z, Hou S, Yang X, Duan Y, Han J, Wang Q, Liao C.
J Med Chem (2022) 65 : 6356 -6389
PubMed 35235745 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.92 5.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4297488 CT-7001 2.0 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4297488 CT-7001 IC50 = 1200.0 nM 5.92