Assay Detail
Binding
CHEMBL5146303
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK1 (unknown origin) expressed in baculovirus expression system using biotinylated peptide substrate incubated for 1 hr in presence of P33-gamma-ATP by scintillation counter method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Lessons Learned from Past Cyclin-Dependent Kinase Drug Discovery Efforts.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.05 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL191003 | JNJ-7706621 | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL191003 | JNJ-7706621 | IC50 | = | 9.0 | nM | 8.05 |