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Assay Detail

CHEMBL5146618

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against Enterococcus faecium assessed as bacterial growth inhibition incubated for 5 hrs by bromocresol purple dye based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterococcus faecium
Confidence 1 — Organism
Curated By Autocuration

Target

Enterococcus faecium (CHEMBL357)
Type ORGANISM
Organism Enterococcus faecium

Publication

Antimicrobial Prenylated Isoflavones from the Leaves of the Amazonian Medicinal Plant <i>Vatairea guianensis</i> Aubl.
Çiçek SS, Galarza Pérez M, Wenzel-Storjohann A, Bezerra RM, Segovia JFO, Girreser U, Kanzaki I, Tasdemir D.
J Nat Prod (2022) 85 : 927 -935
PubMed 35271771 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 5.07 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL174 AMPICILLIN 4.0 1 6.22
CHEMBL5174986 1 4.89
CHEMBL5180194 1 4.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL174 AMPICILLIN IC50 = 600.0 nM 6.22
CHEMBL5174986 IC50 = 12800.0 nM 4.89
CHEMBL5180194 IC50 = 80600.0 nM 4.09