Assay Detail
Functional
CHEMBL5146805
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against SARS-CoV-2 isolate USA-WA1/2020 infected in Calu-3 cells preincubated for 24 hrs followed by viral infection and measured after 48 hrs by Hoechst 33342 staining based microscopic method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
SARS-CoV-2 (CHEMBL4303835) ↗| Type | ORGANISM |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
Publication
Marine Natural Products as Leads against SARS-CoV-2 Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.76 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4065616 | REMDESIVIR | 4.0 | 1 | 6.52 |
| CHEMBL5184812 | — | — | 1 | 5.96 |
| CHEMBL504264 | AUREOL | — | 1 | 5.40 |
| CHEMBL1257967 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4065616 | REMDESIVIR | EC50 | = | 300.0 | nM | 6.52 |
| CHEMBL5184812 | — | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL504264 | AUREOL | EC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL1257967 | — | EC50 | = | 6900.0 | nM | 5.16 |