Assay Detail
Functional
CHEMBL5146832
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Antiviral activity against Rhinovirus A1B infected in human H1-HeLa cells assessed as reduction in virus induced cytopathic effect incubated for 3 days by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | rhinovirus A1B |
| Cell Type | H1-HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enteroviral replication inhibition by N-Alkyl triazolopyrimidinone derivatives through a non-capsid binding mode.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.17 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29609 | PLECONARIL | 2.0 | 1 | 6.62 |
| CHEMBL5173613 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29609 | PLECONARIL | EC50 | = | 240.0 | nM | 6.62 |
| CHEMBL5173613 | — | EC50 | = | 1900.0 | nM | 5.72 |