Assay Detail
Functional
CHEMBL5146837
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Rhinovirus B27 infected in human H1-HeLa cells assessed as reduction in virus induced cytopathic effect incubated for 3 days by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rhinovirus B |
| Cell Type | H1-HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Enteroviral replication inhibition by N-Alkyl triazolopyrimidinone derivatives through a non-capsid binding mode.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.80 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5173613 | — | — | 1 | 5.80 |
| CHEMBL29609 | PLECONARIL | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5173613 | — | EC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL29609 | PLECONARIL | EC50 | - | — | - |