Assay Detail
Binding
CHEMBL5146984
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Mycobacterium tuberculosis H37Rv PDF expressed in Escherichia coli using N-formyl-methionine-alanine-serine as substrate incubated for 2.5 mins by fluorescence based microplate reader analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis and antibacterial activity against pathogenic mycobacteria of conjugated hydroxamic acids, hydrazides and O-alkyl/O-acyl protected hydroxamic derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.36 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL431210 | — | — | 1 | 7.62 |
| CHEMBL308333 | ACTINONIN | — | 1 | 7.30 |
| CHEMBL464061 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL431210 | — | IC50 | = | 23.9 | nM | 7.62 |
| CHEMBL308333 | ACTINONIN | IC50 | = | 50.5 | nM | 7.30 |
| CHEMBL464061 | — | IC50 | = | 69.5 | nM | 7.16 |