Assay Detail
Functional
CHEMBL5147364
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of interferon gamma production in human Vgamma9Vdelta2 T cells pretreated with K562 cells followed by compound washout and cocultured with Vgamma9Vdelta2 T cells and measured after 60 mins by ELISA
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Vgamma9Vdelta2 T cell |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Efficiency of bis-amidate phosphonate prodrugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.44 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5191573 | — | — | 1 | 7.64 |
| CHEMBL4088948 | — | — | 1 | 7.52 |
| CHEMBL4204044 | — | — | 1 | 6.64 |
| CHEMBL5195694 | — | — | 1 | 5.24 |
| CHEMBL5170932 | — | — | 1 | 5.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5191573 | — | EC50 | = | 23.0 | nM | 7.64 |
| CHEMBL4088948 | — | EC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4204044 | — | EC50 | = | 230.0 | nM | 6.64 |
| CHEMBL5195694 | — | EC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL5170932 | — | EC50 | = | 7200.0 | nM | 5.14 |