Assay Detail
Binding
CHEMBL5148487
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human FXR2 expressed in HEK293 cells coexpressing IBABP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of BMS-986339, a Pharmacologically Differentiated Farnesoid X Receptor Agonist for the Treatment of Nonalcoholic Steatohepatitis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.08 | 7.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4862974 | — | — | 1 | 7.08 |
| CHEMBL5182534 | — | — | 1 | 7.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4862974 | — | EC50 | = | 84.0 | nM | 7.08 |
| CHEMBL5182534 | — | EC50 | = | 85.0 | nM | 7.07 |