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Assay Detail

CHEMBL5150299

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human PI3K beta
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Phosphatidylinositol 3-kinase regulatory subunit beta (CHEMBL4437)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small-Molecule Kinase Inhibitors for the Treatment of Nononcologic Diseases.
Xie Z, Yang X, Duan Y, Han J, Liao C.
J Med Chem (2021) 64 : 1283 -1345
PubMed 33481605 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.20 6.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4434674 1 6.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4434674 IC50 = 630.0 nM 6.20