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Assay Detail

CHEMBL5150443

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Functional
Antiproliferative activity against human ALL-SIL cells assessed as cell growth inhibition incubated for 4 days by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type ALL-SIL
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application.
Wang S, Yuan XH, Wang SQ, Zhao W, Chen XB, Yu B.
Eur J Med Chem (2021) 214 : 113218 -113218
PubMed 33540357 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.17 7.17

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1201112 NELARABINE 4.0 1 7.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1201112 NELARABINE IC50 = 67.0 nM 7.17