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Assay Detail

CHEMBL5150945

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of MERS-CoV Main protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Middle East respiratory syndrome-related coronavirus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities.
Robello M, Barresi E, Baglini E, Salerno S, Taliani S, Settimo FD.
J Med Chem (2021) 64 : 3508 -3545
PubMed 33764065 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5075209 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5075209 IC50 = 580.0 nM 6.24