Assay Detail
Functional
CHEMBL5151276
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Anticancer activity against human MCF7 cells assessed as inhibition of cell growth by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of cytotoxic natural products from Red Sea sponges: Structure and synthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.58 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 8.92 |
| CHEMBL5188813 | — | — | 1 | 8.89 |
| CHEMBL5196791 | — | — | 1 | 8.62 |
| CHEMBL228073 | — | — | 1 | 8.54 |
| CHEMBL5178910 | — | — | 1 | 8.40 |
| CHEMBL5176424 | — | — | 1 | 8.34 |
| CHEMBL5175638 | — | — | 1 | 8.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL5188813 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL5196791 | — | IC50 | = | 2.4 | nM | 8.62 |
| CHEMBL228073 | — | IC50 | = | 2.9 | nM | 8.54 |
| CHEMBL5178910 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL5176424 | — | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL5175638 | — | IC50 | = | 4.8 | nM | 8.32 |