Assay Detail
Functional
CHEMBL5151307
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Cytotoxicity against human Jurkat-TAg cells assessed as cell growth inhibition measured after 48 hrs
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Jurkat-TAg |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Spliceostatins and Derivatives: Chemical Syntheses and Biological Properties of Potent Splicing Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.76 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5169545 | — | — | 1 | 8.80 |
| CHEMBL494107 | — | — | 1 | 8.70 |
| CHEMBL5179398 | — | — | 1 | 5.77 |
| CHEMBL5202434 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5169545 | — | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL494107 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL5179398 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL5202434 | — | IC50 | > | 4000.0 | nM | - |