Assay Detail
Binding
CHEMBL5151552
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Inhibition of CDK2/cyclin E (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.18 | 6.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1208600 | — | — | 1 | 6.82 |
| CHEMBL216543 | — | — | 1 | 6.60 |
| CHEMBL1276127 | INDIRUBIN | 2.0 | 1 | 5.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1208600 | — | IC50 | = | 150.0 | nM | 6.82 |
| CHEMBL216543 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1276127 | INDIRUBIN | IC50 | = | 7500.0 | nM | 5.12 |