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Assay Detail

CHEMBL5151589

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Functional
Antiproliferative activity against human SNU-638 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type SNU-638
Confidence 1 — Organism
Curated By Autocuration

Target

SNU-638 (CHEMBL614935)
Type CELL-LINE
Organism Homo sapiens

Publication

Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship.
Wang H, Wang Z, Wei C, Wang J, Xu Y, Bai G, Yao Q, Zhang L, Chen Y.
Eur J Med Chem (2021) 223 : 113652 -113652
PubMed 34161865 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.44 5.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1077291 1 5.68
CHEMBL513703 1 5.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1077291 IC50 = 2100.0 nM 5.68
CHEMBL513703 IC50 = 6500.0 nM 5.19