Assay Detail
Toxicity
CHEMBL5151591
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Cytotoxicity against rat RK3E cells harboring RAS assessed as cell growth inhibition measured after 24 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Rattus norvegicus |
| Cell Type | RK3E |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.49 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL471250 | — | — | 1 | 6.00 |
| CHEMBL1077291 | — | — | 1 | 5.29 |
| CHEMBL513703 | — | — | 1 | 5.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL471250 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1077291 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL513703 | — | IC50 | = | 6400.0 | nM | 5.19 |