Assay Detail
Functional
CHEMBL5151618
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Antiproliferative activity against human LXFL 529 cells assessed as cell growth inhibition
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | LXFL 529 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.10 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1165371 | — | — | 1 | 6.30 |
| CHEMBL1276317 | — | — | 1 | 6.05 |
| CHEMBL4100916 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1165371 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL1276317 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL4100916 | — | IC50 | = | 1100.0 | nM | 5.96 |