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Assay Detail

CHEMBL5151659

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of GSK3 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 5 — Multiple protein complex / RNA
Curated By Autocuration

Target

Glycogen synthase kinase-3 (CHEMBL2095188)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship.
Wang H, Wang Z, Wei C, Wang J, Xu Y, Bai G, Yao Q, Zhang L, Chen Y.
Eur J Med Chem (2021) 223 : 113652 -113652
PubMed 34161865 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.89 8.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3216659 1 8.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3216659 IC50 = 1.3 nM 8.89