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Assay Detail

CHEMBL5151759

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Functional
Agonist activity at human TAAR1 stably expressed in HEK293 cells incubated for 30 mins by cAMP assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Trace amine-associated receptor 1 (CHEMBL5857)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The Alkaloids from <i>Lophophora diffusa</i> and Other "False Peyotes".
Chan CB, Poulie CBM, Wismann SS, Soelberg J, Kristensen JL.
J Nat Prod (2021) 84 : 2398 -2407
PubMed 34264089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.00 6.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL11608 TYRAMINE 3.0 1 6.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL11608 TYRAMINE EC50 = 990.0 nM 6.00