Assay Detail
Binding
CHEMBL5151820
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Inhibition of Zika virus RNA-dependent RNA polymerase activity
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Zika virus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.40 | 5.87 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4065616 | REMDESIVIR | 4.0 | 1 | 5.87 |
| CHEMBL374931 | — | — | 1 | 5.28 |
| CHEMBL2057532 | — | — | 1 | 5.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4065616 | REMDESIVIR | IC50 | = | 1360.0 | nM | 5.87 |
| CHEMBL374931 | — | IC50 | = | 5260.0 | nM | 5.28 |
| CHEMBL2057532 | — | IC50 | = | 8920.0 | nM | 5.05 |