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Assay Detail

CHEMBL5151825

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity DENV infected in African green monkey Vero 76 cells assessed as virus-induced cytopathic effect
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Dengue virus
Cell Type Vero 76
Confidence 1 — Organism
Curated By Autocuration

Target

Dengue virus (CHEMBL613757)
Type ORGANISM
Organism Dengue virus

Publication

Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors.
Nascimento IJDS, Santos-Júnior PFDS, Aquino TM, Araújo-Júnior JX, Silva-Júnior EFD.
Eur J Med Chem (2021) 224 : 113698 -113698
PubMed 34274831 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.24 7.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3596788 1 7.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3596788 EC50 = 57.0 nM 7.24