Assay Detail
Binding
CHEMBL5151853
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MLL1 (unknown origin) histone methyltransferase activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Histone-lysine N-methyltransferase 2A (CHEMBL1293299) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting WD Repeat-Containing Protein 5 (WDR5): A Medicinal Chemistry Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.21 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5183439 | — | — | 1 | 7.70 |
| CHEMBL5172154 | — | — | 1 | 6.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5183439 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5172154 | — | IC50 | = | 190.0 | nM | 6.72 |