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Assay Detail

CHEMBL5152233

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Influenza A virus H5N1 Neuraminidase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Influenza A virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Identification of C5-NH<sub>2</sub> Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability.
Ju H, Murugan NA, Hou L, Li P, Guizzo L, Zhang Y, Bertagnin C, Kong X, Kang D, Jia R, Ma X, Du R, Poongavanam V, Loregian A, Huang B, Liu X, Zhan P.
J Med Chem (2021) 64 : 17992 -18009
PubMed 34735766 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.02 9.02

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4287425 1 9.02

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4287425 IC50 = 0.96 nM 9.02