Assay Detail
Binding
CHEMBL5152354
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Binding affinity to GSK-3 (unknown origin) assessed as inhibition constant
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
The Repertoire of Small-Molecule PET Probes for Neuroinflammation Imaging: Challenges and Opportunities beyond TSPO.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.53 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5174733 | — | — | 1 | 9.22 |
| CHEMBL5176600 | — | — | 1 | 8.31 |
| CHEMBL3582401 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5174733 | — | Ki | = | 0.6 | nM | 9.22 |
| CHEMBL5176600 | — | Ki | = | 4.9 | nM | 8.31 |
| CHEMBL3582401 | — | Ki | = | 9.0 | nM | 8.05 |