Assay Detail
Binding
CHEMBL5152408
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to NTCP (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Hepatic sodium/bile acid cotransporter (CHEMBL5287) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Inhibiting Sodium Taurocholate Cotransporting Polypeptide in HBV-Related Diseases: From Biological Function to Therapeutic Potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.75 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1513 | IRBESARTAN | 4.0 | 1 | 4.92 |
| CHEMBL163 | RITONAVIR | 4.0 | 1 | 4.74 |
| CHEMBL1138 | EZETIMIBE | 4.0 | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1513 | IRBESARTAN | Ki | = | 11900.0 | nM | 4.92 |
| CHEMBL163 | RITONAVIR | Ki | = | 18400.0 | nM | 4.74 |
| CHEMBL1138 | EZETIMIBE | Ki | = | 25000.0 | nM | 4.60 |