Assay Detail
Functional
CHEMBL5152489
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antitumor activity against patient-derived Lung cancer cell line xenografted in NMRI nu/nu mouse LXFA-983 model assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Lung cancer cell line |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeting Extracellular Signal-Regulated Protein Kinase 1/2 (ERK1/2) in Cancer: An Update on Pharmacological Small-Molecule Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.10 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5183609 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5183609 | — | IC50 | = | 800.0 | nM | 6.10 |