Assay Detail
Binding
CHEMBL5153320
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Binding affinity to IDO1 (unknown origin) assessed as dissociation constant by bio-layer interferometry assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.16 | 6.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4161733 | — | — | 1 | 6.33 |
| CHEMBL5192805 | — | — | 1 | 6.19 |
| CHEMBL5189195 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4161733 | — | Kd | = | 470.0 | nM | 6.33 |
| CHEMBL5192805 | — | Kd | = | 640.0 | nM | 6.19 |
| CHEMBL5189195 | — | Kd | = | 1100.0 | nM | 5.96 |