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Assay Detail

CHEMBL5153445

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antitumor activity against BCL6 dependent human OCILY7 cells assessed as cell growth inhibition
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type OCI-Ly7
Confidence 1 — Organism
Curated By Autocuration

Target

OCI-Ly7 (CHEMBL4523564)
Type CELL-LINE
Organism Homo sapiens

Publication

B-cell Lymphoma 6 Inhibitors: Current Advances and Prospects of Drug Development for Diffuse Large B-cell Lymphomas.
Gu H, He J, Li Y, Mi D, Guan T, Guo W, Liu B, Chen Y.
J Med Chem (2022) 65 : 15559 -15583
PubMed 36441945 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5204980 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5204980 IC50 = 1100.0 nM 5.96