Assay Detail
Binding
CHEMBL5155148
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human recombinant CK2alpha2beta2 using RRRDDDSDDD peptide as substrate in presence of [gamma-33P]ATP incubated for 40 mins by radiometric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Molecular Plasticity of Crystalline CK2α' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 9.65 | 9.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1230165 | SILMITASERTIB | 2.0 | 1 | 9.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1230165 | SILMITASERTIB | Ki | = | 0.223 | nM | 9.65 |