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Assay Detail

CHEMBL5155181

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antischistosomal activity against juvenile stage of Schistosoma mansoni measured after 72 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Schistosoma mansoni
Confidence 1 — Organism
Curated By Autocuration

Target

Schistosoma mansoni (CHEMBL612893)
Type ORGANISM
Organism Schistosoma mansoni

Publication

Anti-schistosomal activities of quinoxaline-containing compounds: From hit identification to lead optimisation.
Padalino G, El-Sakkary N, Liu LJ, Liu C, Harte DSG, Barnes RE, Sayers E, Forde-Thomas J, Whiteland H, Bassetto M, Ferla S, Johnson G, Jones AT, Caffrey CR, Chalmers I, Brancale A, Hoffmann KF.
Eur J Med Chem (2021) 226 : 113823 -113823
PubMed 34536671 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL529407 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL529407 EC50 = 201.0 nM 6.70