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Assay Detail

CHEMBL5155889

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to CK1a1 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Casein kinase I isoform alpha (CHEMBL2793)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

High-Throughput Screening Platform in Postnatal Heart Cells and Chemical Probe Toolbox to Assess Cardiomyocyte Proliferation.
Carrillo García C, Becker C, Forster M, Lohmann S, Freitag P, Laufer S, Sievers S, Fleischmann BK, Hesse M, Schade D.
J Med Chem (2022) 65 : 1505 -1524
PubMed 34818008 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.25 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL97162 1 6.30
CHEMBL280317 1 6.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL97162 Ki = 501.0 nM 6.30
CHEMBL280317 Ki = 650.0 nM 6.19