Assay Detail
Functional
CHEMBL5156013
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Antiproliferative activity against human U2OS cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U2OS |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel 2-phenyl-3-(Pyridin-2-yl) thiazolidin-4-one derivatives as potent inhibitors for proliferation of osteosarcoma cells in vitro and in vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.58 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5180080 | — | — | 1 | 7.58 |
| CHEMBL5171477 | — | — | 1 | - |
| CHEMBL5191134 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5180080 | — | IC50 | = | 26.5 | nM | 7.58 |
| CHEMBL5171477 | — | IC50 | - | — | - | |
| CHEMBL5191134 | — | IC50 | - | — | - |