Assay Detail
Functional
CHEMBL5156015
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human SW1353 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW1353 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel 2-phenyl-3-(Pyridin-2-yl) thiazolidin-4-one derivatives as potent inhibitors for proliferation of osteosarcoma cells in vitro and in vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5180080 | — | — | 1 | 7.70 |
| CHEMBL5171477 | — | — | 1 | - |
| CHEMBL5191134 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5180080 | — | IC50 | = | 19.9 | nM | 7.70 |
| CHEMBL5171477 | — | IC50 | - | — | - | |
| CHEMBL5191134 | — | IC50 | - | — | - |