Assay Detail
Functional
CHEMBL5156017
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human SJSA-1 cells assessed as cell growth inhibition measured after 72 hrs by CCK-8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SJSA-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel 2-phenyl-3-(Pyridin-2-yl) thiazolidin-4-one derivatives as potent inhibitors for proliferation of osteosarcoma cells in vitro and in vivo.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.35 | 7.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5171477 | — | — | 1 | 7.48 |
| CHEMBL5180080 | — | — | 1 | 7.21 |
| CHEMBL5191134 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5171477 | — | IC50 | = | 33.2 | nM | 7.48 |
| CHEMBL5180080 | — | IC50 | = | 62.2 | nM | 7.21 |
| CHEMBL5191134 | — | IC50 | - | — | - |