Assay Detail
Binding
CHEMBL5156170
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human HDAC9 using fluorogenic substrate by fluorescence microplate reader assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, biochemical evaluation, radiolabeling and in vivo imaging with high affinity class-IIa histone deacetylase inhibitor for molecular imaging and targeted therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.84 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3692689 | — | — | 1 | 9.05 |
| CHEMBL4751615 | — | — | 1 | 8.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3692689 | — | IC50 | = | 0.9 | nM | 9.05 |
| CHEMBL4751615 | — | IC50 | = | 2.4 | nM | 8.62 |