Assay Detail
Binding
CHEMBL5157633
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HDAC6 (unknown origin) using trypsin and Ac-peptide as substrates
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel PHD2/HDACs hybrid inhibitors protect against cisplatin-induced acute kidney injury.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.97 | 8.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | 4.0 | 1 | 8.14 |
| CHEMBL5172182 | — | — | 1 | 7.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL98 | VORINOSTAT | IC50 | = | 7.25 | nM | 8.14 |
| CHEMBL5172182 | — | IC50 | = | 15.98 | nM | 7.80 |