Assay Detail
Binding
CHEMBL5158218
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Agonist activity at human PPARdelta expressed in HEK293 cells by luciferase/beta-galactosidase reporter gene assay
12
Total Activities
12
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Emax | 11 | - | - |
| EC50 | 1 | 8.46 | 8.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL38508 | — | — | 1 | 8.46 |
| CHEMBL33778 | ANACARDIC ACID | — | 1 | - |
| CHEMBL5177968 | — | — | 1 | - |
| CHEMBL5182467 | — | — | 1 | - |
| CHEMBL5198240 | — | — | 1 | - |
| CHEMBL5187974 | — | — | 1 | - |
| CHEMBL5191595 | — | — | 1 | - |
| CHEMBL5192854 | — | — | 1 | - |
| CHEMBL5196042 | — | — | 1 | - |
| CHEMBL5191280 | — | — | 1 | - |
| CHEMBL111077 | MYRISTIC ACID | -1.0 | 1 | - |
| CHEMBL8659 | OLEIC ACID | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL38508 | — | EC50 | = | 3.5 | nM | 8.46 |
| CHEMBL33778 | ANACARDIC ACID | Emax | = | 68.0 | uM | - |
| CHEMBL5177968 | — | Emax | > | 50.0 | uM | - |
| CHEMBL5182467 | — | Emax | > | 100.0 | uM | - |
| CHEMBL5198240 | — | Emax | = | 10.0 | uM | - |
| CHEMBL5187974 | — | Emax | = | 33.0 | uM | - |
| CHEMBL5191595 | — | Emax | = | 7.1 | uM | - |
| CHEMBL5192854 | — | Emax | > | 100.0 | uM | - |
| CHEMBL5196042 | — | Emax | = | 70.0 | uM | - |
| CHEMBL5191280 | — | Emax | = | 21.0 | uM | - |
| CHEMBL111077 | MYRISTIC ACID | Emax | = | 51.0 | uM | - |
| CHEMBL8659 | OLEIC ACID | Emax | = | 47.0 | uM | - |