Assay Detail
Functional
CHEMBL5158260
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human NPBWR1 expressed in CHO cells measured by LANCE Ultra cAMP kit-based TR-FRET assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Neuropeptides B/W receptor type 1 (CHEMBL1293293) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Neuropeptide B/W receptor 1 peptidomimetic agonists: Structure-activity relationships and plasma stability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 8.40 | 8.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5187335 | — | — | 1 | 8.57 |
| CHEMBL5170622 | — | — | 1 | 8.46 |
| CHEMBL5204006 | — | — | 1 | 8.29 |
| CHEMBL5197385 | — | — | 1 | 8.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5187335 | — | EC50 | = | 2.7 | nM | 8.57 |
| CHEMBL5170622 | — | EC50 | = | 3.5 | nM | 8.46 |
| CHEMBL5204006 | — | EC50 | = | 5.1 | nM | 8.29 |
| CHEMBL5197385 | — | EC50 | = | 5.5 | nM | 8.26 |