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Assay Detail

CHEMBL5158316

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of DMH-1 induced cardiogenesis in mouse ESC transfected with Myh6-GFP
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Embryonic stem cell
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Probing Embryonic Development Enables the Discovery of Unique Small-Molecule Bone Morphogenetic Protein Potentiators.
Wesseler F, Riege D, Puthanveedu M, Halver J, Müller E, Bertrand J, Antonchick AP, Sievers S, Waldmann H, Schade D.
J Med Chem (2022) 65 : 3978 -3990
PubMed 35108017 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.70 6.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5205081 1 6.70
CHEMBL4639853 1 6.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5205081 IC50 = 200.0 nM 6.70
CHEMBL4639853 IC50 = 200.0 nM 6.70