Assay Detail
Functional
CHEMBL5158784
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Cytotoxicity against human Bel-7402 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Bel-7402 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Semisynthesis and biological evaluation of (+)-sclerotiorin derivatives as antitumor agents for the treatment of hepatocellular carcinoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.07 | 9.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | 4.0 | 1 | 9.43 |
| CHEMBL5180078 | — | — | 1 | 8.94 |
| CHEMBL5182429 | — | — | 1 | 8.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359744 | DOXORUBICIN HYDROCHLORIDE | IC50 | = | 0.369 | nM | 9.43 |
| CHEMBL5180078 | — | IC50 | = | 1.15 | nM | 8.94 |
| CHEMBL5182429 | — | IC50 | = | 1.45 | nM | 8.84 |