Assay Detail
Functional
CHEMBL5158786
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Cytotoxicity against human Biu-87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | BIU-87 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Semisynthesis and biological evaluation of (+)-sclerotiorin derivatives as antitumor agents for the treatment of hepatocellular carcinoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.54 | 8.56 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5180078 | — | — | 1 | 8.56 |
| CHEMBL5182429 | — | — | 1 | 8.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5180078 | — | IC50 | = | 2.76 | nM | 8.56 |
| CHEMBL5182429 | — | IC50 | = | 3.1 | nM | 8.51 |