Assay Detail
Binding
CHEMBL5159015
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PKCbeta1 (unknown origin) by IMAP kinase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel Aurora A and Protein Kinase C (α, β1, β2, and θ) Multitarget Inhibitors: Impact of Selenium Atoms on the Potency and Selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.76 | 9.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL565612 | SOTRASTAURIN | 2.0 | 1 | 9.19 |
| CHEMBL91829 | RUBOXISTAURIN | 3.0 | 1 | 8.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL565612 | SOTRASTAURIN | IC50 | = | 0.64 | nM | 9.19 |
| CHEMBL91829 | RUBOXISTAURIN | IC50 | = | 4.7 | nM | 8.33 |